Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
spg11SPG11 vesicle trafficking associated, spatacsin. (2269 aa)    
Predicted Functional Partners:
zfyve26
Zinc finger, FYVE domain containing 26.
   
 
 0.996
ap5z1
Adaptor related protein complex 5 subunit zeta 1.
    
 
 0.981
ap5m1
Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
    
 
 0.968
ap5s1
Adaptor related protein complex 5 subunit sigma 1.
    
 
 0.956
Zfyve21
Uncharacterized protein.
   
 
 0.908
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.828
spg21
SPG21 abhydrolase domain containing, maspardin.
      
 0.783
atxn2
Ataxin 2.
   
  
 0.765
pla2g6
Phospholipase A2, group VI (cytosolic, calcium-independent).
      
 0.758
LOC103467077
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
      
 0.758
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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