STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103476464Cyclic GMP-AMP synthase. (570 aa)    
Predicted Functional Partners:
LOC103472993
Mab-21 domain-containing protein.
  
  
 
0.907
sting1
Transmembrane protein 173.
  
 
 0.709
tbk1
TANK-binding kinase 1.
      
 0.695
LOC103481249
Interferon regulatory factor 3.
      
 0.665
mavs
CARD_2 domain-containing protein.
      
 0.593
irf7
Interferon regulatory factor 7.
      
 0.570
LOC103475016
Thyroid hormone responsive.
    
  0.547
ace2
Angiotensin-converting enzyme.
      
 0.545
DDX41
DEAD-box helicase 41.
      
 0.524
sae1
SUMO1 activating enzyme subunit 1.
      
 0.521
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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