STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103461931HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a. (1331 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
  0.756
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.691
gja1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.681
ENSPREP00000024586
Angiomotin.
    
 0.672
wbp2
WW domain binding protein 2.
    
 
 0.652
psma2
Proteasome endopeptidase complex.
    
 0.626
ubb
Uncharacterized protein.
    
 0.621
LOC103473189
Uncharacterized protein.
    
 0.621
ptch2
Patched 2.
    
 0.610
ptch1
Patched 1.
    
 0.610
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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