STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wdr53WD repeat domain 53. (373 aa)    
Predicted Functional Partners:
prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast).
   
 0.961
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast).
   
 0.931
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
   
 0.920
prpf8
Pre-mRNA processing factor 8.
   
 0.916
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
   
 0.911
SART1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
    
 0.899
LSM8
U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
   
 0.895
snrpe
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.894
snrpd3
Small nuclear ribonucleoprotein Sm D3.
   
 0.887
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.
    
 0.885
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.