Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgap1Post-GPI attachment to proteins 1. (931 aa)    
Predicted Functional Partners:
LOC103461434
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
    
 0.992
mppe1
Metallophosphoesterase 1.
    
 0.965
LOC103481806
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
    
 0.961
pigk
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.958
pigt
Phosphatidylinositol glycan anchor biosynthesis, class T.
     
 0.958
gpaa1
Glycosylphosphatidylinositol anchor attachment 1.
     
 0.955
pigs
Phosphatidylinositol glycan anchor biosynthesis, class S.
    
 0.950
pigu
Phosphatidylinositol glycan anchor biosynthesis, class U.
     
 0.932
tmed10
Transmembrane p24 trafficking protein 10.
    
 
 0.905
pigg
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 
 0.808
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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