mlh1 protein (Poecilia reticulata) - STRING interaction network

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[Homology]

Score

mlh1

MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa)

Predicted Functional Partners:

pms2

0.999

msh2

0.999

msh6

0.999

pms1

0.997

msh3

0.997

fan1

0.997

exo1

0.996

mlh3

0.995

brca1

0.990

pcna

0.988

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
brca1	exo1	ENSPREP00000033076	ENSPREP00000027206	Uncharacterized protein.	Exonuclease 1.	0.933
brca1	mlh1	ENSPREP00000033076	ENSPREP00000002003	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.990
brca1	msh2	ENSPREP00000033076	ENSPREP00000007571	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.982
brca1	msh3	ENSPREP00000033076	ENSPREP00000018450	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.660
brca1	msh6	ENSPREP00000033076	ENSPREP00000034111	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.949
brca1	pcna	ENSPREP00000033076	ENSPREP00000018020	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.798
brca1	pms1	ENSPREP00000033076	ENSPREP00000001469	Uncharacterized protein.	PMS1 homolog 1, mismatch repair system component.	0.456
brca1	pms2	ENSPREP00000033076	ENSPREP00000006640	Uncharacterized protein.	PMS1 homolog 2, mismatch repair system component.	0.666
exo1	brca1	ENSPREP00000027206	ENSPREP00000033076	Exonuclease 1.	Uncharacterized protein.	0.933
exo1	fan1	ENSPREP00000027206	ENSPREP00000022191	Exonuclease 1.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.451
exo1	mlh1	ENSPREP00000027206	ENSPREP00000002003	Exonuclease 1.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.996
exo1	mlh3	ENSPREP00000027206	ENSPREP00000014130	Exonuclease 1.	MutL homolog 3 (E. coli).	0.767
exo1	msh2	ENSPREP00000027206	ENSPREP00000007571	Exonuclease 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.996
exo1	msh3	ENSPREP00000027206	ENSPREP00000018450	Exonuclease 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.935
exo1	msh6	ENSPREP00000027206	ENSPREP00000034111	Exonuclease 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.974
exo1	pcna	ENSPREP00000027206	ENSPREP00000018020	Exonuclease 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
exo1	pms1	ENSPREP00000027206	ENSPREP00000001469	Exonuclease 1.	PMS1 homolog 1, mismatch repair system component.	0.962
exo1	pms2	ENSPREP00000027206	ENSPREP00000006640	Exonuclease 1.	PMS1 homolog 2, mismatch repair system component.	0.978
fan1	exo1	ENSPREP00000022191	ENSPREP00000027206	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Exonuclease 1.	0.451
fan1	mlh1	ENSPREP00000022191	ENSPREP00000002003	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.997