STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tyw5tRNA-yW synthesizing protein 5. (260 aa)    
Predicted Functional Partners:
use1
Unconventional SNARE in the ER 1 homolog (S. cerevisiae).
    
   0.894
trmt5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
      
 0.853
trmt12
tRNA methyltransferase 12 homolog.
 
    
 0.808
LOC103475137
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae).
  
   
 0.798
clg2h2orf69
Zgc:153521.
      
 0.728
tyw3
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae).
      
 0.724
JMJD8
Jumonji domain containing 8.
      
 0.680
RPL27A
Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.
      
 0.656
slc38a7
Solute carrier family 38 member 7.
      
 0.650
rps6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
    
  0.646
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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