STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spcs2Signal peptidase complex subunit 2. (210 aa)    
Predicted Functional Partners:
spcs1
Signal peptidase complex subunit 1.
   
 0.999
spcs3
Signal peptidase complex subunit 3.
   
 0.999
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 0.989
grp
Uncharacterized protein.
   
 0.974
sec63
SEC63 homolog, protein translocation regulator.
   
 
 0.945
sec62
SEC62 homolog, preprotein translocation factor.
   
 
 0.938
ddost
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 0.930
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 
 0.918
ssr3
Signal sequence receptor, gamma.
   
 
 0.894
immp2l
Mitochondrial inner membrane protease subunit.
   
 0.868
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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