STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
creb5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (491 aa)    
Predicted Functional Partners:
rps6ka5
Ribosomal protein S6 kinase.
   
 0.913
ENSPREP00000002835
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.777
ENSPREP00000020034
JunE proto-oncogene, AP-1 transcription factor subunit.
   
 0.777
prkaca
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.698
LOC103468785
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.698
LOC103479663
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
    
 0.698
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.698
c-fos
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
    
 0.669
spc25
SPC25 component of NDC80 kinetochore complex.
   
 0.643
fosl2
Fos-like antigen 2.
    
0.642
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.