STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH2B2SH2B adaptor protein 2. (689 aa)    
Predicted Functional Partners:
LOC103476312
Uncharacterized protein.
    
 0.968
insr
Insulin receptor a.
    
 0.962
grb2
Growth factor receptor-bound protein 2b.
    
 0.799
tyk2
Tyrosine-protein kinase.
    
 0.731
LOC103469946
Tyrosine-protein kinase.
    
 0.731
jak3
Tyrosine-protein kinase.
    
 0.731
jak2
Tyrosine-protein kinase.
    
 0.731
jak1
Tyrosine-protein kinase.
    
 0.731
LOC103477907
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.704
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.704
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.