STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxo25F-box protein 25. (365 aa)    
Predicted Functional Partners:
myog
Myogenin.
    
 
 0.940
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.931
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.918
rpl13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
      
 0.903
fbxo32
F-box protein 32.
  
  
 
0.901
eif3f
Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
    
 0.731
fbxw5
F-box and WD repeat domain containing 5.
     
 0.724
LOC103478877
Matrix metallopeptidase 14b (membrane-inserted).
      
 0.714
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.707
fbxl2
F-box and leucine-rich repeat protein 2.
   
 
 0.661
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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