STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
herc4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1011 aa)    
Predicted Functional Partners:
trip12
Thyroid hormone receptor interactor 12.
   
 
0.716
LOC103473220
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.634
ifih1
Interferon induced with helicase C domain 1.
   
 
 0.551
pde6d
60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family.
      
 0.513
dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58.
   
 
 0.482
LOC103469622
Whirlin b.
      
 0.475
whrn
Whirlin a.
      
 0.475
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae).
   
 0.470
LOC103464541
Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.448
uba6
Ubiquitin like modifier activating enzyme 6.
   
 0.448
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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