STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
herc4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1011 aa)    
Predicted Functional Partners:
LOC103473220
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.742
nup133
Nucleoporin 133.
   
  
 0.672
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.663
rps27a
Ribosomal protein S27a.
    
 0.628
rsad2
Radical S-adenosyl methionine domain containing 2.
   
 
 0.613
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.573
LOC103456942
Structural maintenance of chromosomes flexible hinge domain containing 1.
   
  
 0.539
LOC103456865
Structural maintenance of chromosomes flexible hinge domain containing 1.
   
  
 0.539
LOC103481249
Interferon regulatory factor 3.
   
 0.534
becn1
Beclin 1, autophagy related.
    
  0.519
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.