STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppm1kProtein phosphatase, Mg2+/Mn2+ dependent, 1K. (383 aa)    
Predicted Functional Partners:
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
   
 0.819
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.761
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.761
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.712
LOC103476976
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.712
LOC103477109
Polycystic kidney disease 2-like 1.
      
 0.550
sec31b
SEC31 homolog B, COPII coat complex component.
     
 0.540
dld
Dihydrolipoyl dehydrogenase.
   
 0.527
LOC103462385
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.525
mtfmt
Mitochondrial methionyl-tRNA formyltransferase.
  
   0.516
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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