STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ano1Anoctamin. (980 aa)    
Predicted Functional Partners:
spg21
SPG21 abhydrolase domain containing, maspardin.
      
 0.629
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 
 0.619
LOC103463363
Hexosyltransferase.
      
 0.617
lto1
LTO1 maturation factor of ABCE1.
      
 0.616
ENSPREP00000011981
LTO1 maturation factor of ABCE1.
      
 0.616
shcbp1
SHC SH2-domain binding protein 1.
      
 0.599
B3GALT2
Hexosyltransferase.
      
 0.580
gdf15
TGF_BETA_2 domain-containing protein.
      
 0.580
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
    
 
 0.522
slc26a6
Solute carrier family 26 member 6.
      
 0.519
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.