STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (412 aa)    
Predicted Functional Partners:
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.966
LOC103472469
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.946
pik3r3
Uncharacterized protein.
   
 0.940
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
   
 0.940
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
   
 0.940
LOC103478998
Uncharacterized protein.
   
 0.939
LOC103463319
Uncharacterized protein.
   
 0.939
LOC103470780
Uncharacterized protein.
   
 0.939
inpp4b
Inositol polyphosphate-4-phosphatase type II B.
    
 0.927
LOC103473821
Inositol polyphosphate-4-phosphatase type I Ab.
    
 0.927
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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