parva protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

parva

Parvin, alpha a. (372 aa)

Predicted Functional Partners:

ILK

0.993

pxn

0.987

ilk

0.929

LOC103462148

0.918

actb

0.918

rsu1

0.904

parvb

0.901

LOC103464969

0.881

LOC103463567

0.876

LOC103461059

0.861

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ILK	LOC103461059	ENSPREP00000012407	ENSPREP00000019565	Integrin linked kinase.	LIM and senescent cell antigen-like domains 2.	0.898
ILK	LOC103463567	ENSPREP00000012407	ENSPREP00000016488	Integrin linked kinase.	Leupaxin.	0.745
ILK	LOC103464969	ENSPREP00000012407	ENSPREP00000000793	Integrin linked kinase.	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.	0.745
ILK	parva	ENSPREP00000012407	ENSPREP00000002306	Integrin linked kinase.	Parvin, alpha a.	0.993
ILK	parvb	ENSPREP00000012407	ENSPREP00000028056	Integrin linked kinase.	Parvin, beta.	0.996
ILK	pxn	ENSPREP00000012407	ENSPREP00000029599	Integrin linked kinase.	Paxillin b.	0.973
ILK	rsu1	ENSPREP00000012407	ENSPREP00000007388	Integrin linked kinase.	Ras suppressor protein 1.	0.963
LOC103461059	ILK	ENSPREP00000019565	ENSPREP00000012407	LIM and senescent cell antigen-like domains 2.	Integrin linked kinase.	0.898
LOC103461059	ilk	ENSPREP00000019565	ENSPREP00000021435	LIM and senescent cell antigen-like domains 2.	Uncharacterized protein.	0.898
LOC103461059	parva	ENSPREP00000019565	ENSPREP00000002306	LIM and senescent cell antigen-like domains 2.	Parvin, alpha a.	0.861
LOC103461059	parvb	ENSPREP00000019565	ENSPREP00000028056	LIM and senescent cell antigen-like domains 2.	Parvin, beta.	0.861
LOC103461059	rsu1	ENSPREP00000019565	ENSPREP00000007388	LIM and senescent cell antigen-like domains 2.	Ras suppressor protein 1.	0.950
LOC103462148	actb	ENSPREP00000000044	ENSPREP00000027111	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC103462148	parva	ENSPREP00000000044	ENSPREP00000002306	Uncharacterized protein.	Parvin, alpha a.	0.918
LOC103462148	parvb	ENSPREP00000000044	ENSPREP00000028056	Uncharacterized protein.	Parvin, beta.	0.918
LOC103462148	pxn	ENSPREP00000000044	ENSPREP00000029599	Uncharacterized protein.	Paxillin b.	0.928
LOC103463567	ILK	ENSPREP00000016488	ENSPREP00000012407	Leupaxin.	Integrin linked kinase.	0.745
LOC103463567	ilk	ENSPREP00000016488	ENSPREP00000021435	Leupaxin.	Uncharacterized protein.	0.745
LOC103463567	parva	ENSPREP00000016488	ENSPREP00000002306	Leupaxin.	Parvin, alpha a.	0.876
LOC103463567	parvb	ENSPREP00000016488	ENSPREP00000028056	Leupaxin.	Parvin, beta.	0.876