Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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slc8a1Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (949 aa)    
Predicted Functional Partners:
LOC103474423
Sodium channel, voltage-gated, type IV, beta a.
   
  
 0.662
KCNIP1
Potassium voltage-gated channel interacting protein 1.
    
 
 0.660
LOC103473560
Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.659
LOC103468785
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
   
 
  0.653
LOC103479663
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
   
 
  0.653
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 
  0.653
nkain1
Sodium/potassium transporting ATPase interacting 1.
   
  
 0.606
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
      
 0.605
LOC103461054
Uncharacterized protein.
      
 0.603
Kcng2
Potassium voltage-gated channel, subfamily G, member 2; Belongs to the potassium channel family.
      
 0.601
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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