STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plekha8Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8. (565 aa)    
Predicted Functional Partners:
mnat1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
      
 0.809
tmtc4
Transmembrane O-mannosyltransferase targeting cadherins 4.
      
 0.758
trip4
Thyroid hormone receptor interactor 4.
      
 0.758
rspry1
Ring finger and SPRY domain containing 1.
      
 0.707
gpatch3
G patch domain containing 3.
      
 0.701
efcab1
Uncharacterized protein.
      
 0.683
eaf1
EAF domain-containing protein.
      
 0.670
mpeg1
Macrophage expressed 1, tandem duplicate 2.
      
 0.661
Snx20
PX domain-containing protein.
      
 0.644
arl2bp
ADP-ribosylation factor-like 2 binding protein.
      
 0.603
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.