STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
atad1ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family. (365 aa)    
Predicted Functional Partners:
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
  
 
 0.859
pex19
Peroxisomal biogenesis factor 19.
    
 0.847
pex16
Peroxisomal membrane protein PEX16.
     
 0.818
ubxn7
UBX domain protein 7.
   
 0.801
pex12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
    
 0.756
gdap1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
     
 0.742
LOC103460228
ATP-binding cassette, sub-family D (ALD), member 1.
   
 
 0.732
pex2
Peroxisomal biogenesis factor 2.
   
 0.725
pex14
Peroxisomal biogenesis factor 14.
    
 0.721
pxmp2
Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
 
 0.713
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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