STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103458631Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)    
Predicted Functional Partners:
ENSPREP00000032744
Retinoblastoma 1.
   
 0.978
ncor1
Nuclear receptor corepressor 1.
    
 0.967
LOC103462700
SIN3 transcription regulator family member Ab.
   
 0.965
sin3a
SIN3 transcription regulator family member Aa.
   
 0.964
LOC103469257
Recombination signal binding protein for immunoglobulin kappa J region a.
   
 0.958
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.958
LOC103473773
Mothers against decapentaplegic homolog.
   
 0.955
LOC103477474
Mothers against decapentaplegic homolog.
   
 0.955
ncor2
Nuclear receptor corepressor 2.
    
 0.954
LOC103464490
V-ski avian sarcoma viral oncogene homolog b.
   
 0.925
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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