STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103466252Dickkopf WNT signaling pathway inhibitor 3b. (257 aa)    
Predicted Functional Partners:
kremen1
Kringle containing transmembrane protein 1.
    
 0.519
twsg1
Twisted gastrulation BMP signaling modulator 1.
   
  
 0.477
bambi
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.
      
 0.477
LOC103476799
Dickkopf WNT signaling pathway inhibitor 1a.
      
 0.471
LOC103480406
TNF superfamily member 10, like; Belongs to the tumor necrosis factor family.
   
 
 0.462
sfrp1
Secreted frizzled-related protein 1a.
     
 0.443
sfrp5
Secreted frizzled-related protein 5.
     
 0.440
ENSPREP00000030224
PID domain-containing protein.
   
 0.428
bmpr1a
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.419
pdgfra
Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.418
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.