Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxw11F-box and WD repeat domain containing 11a. (562 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.999
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.999
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.998
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.997
fbxo5
F-box protein 5.
    
 0.995
LOC103472282
Uncharacterized protein.
   
 0.989
gli3
Uncharacterized protein.
    
 0.971
gli2
GLI family zinc finger 2a.
    
 0.971
gli1
GLI family zinc finger 1.
    
 0.971
LOC103457154
Uncharacterized protein.
    
 0.971
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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