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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spock1SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (454 aa)    
Predicted Functional Partners:
LOC103468846
TIMP metallopeptidase inhibitor 2b.
     
  0.550
LOC103481516
TIMP metallopeptidase inhibitor 2a.
     
  0.550
LOC103462238
Matrix metallopeptidase 15b.
    
 0.548
LOC103478877
Matrix metallopeptidase 14b (membrane-inserted).
    
 0.548
sparc
Secreted protein, acidic, cysteine-rich (osteonectin).
   
  
 0.479
LOC103476708
SPARC-like 2.
   
  
 0.479
adam10
Uncharacterized protein.
     
 0.461
fam222a
Family with sequence similarity 222 member A.
      
 0.454
LOC103474759
Somatolactin alpha.
    
 0.426
LOC103469032
Chorionic somatomammotropin hormone 1.
    
 0.426
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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