STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103459167Toll-like receptor 7; Belongs to the Toll-like receptor family. (1052 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.969
unc93b1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.858
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.667
LOC103479635
Death domain-containing protein.
   
 0.579
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.574
LOC103480678
Canopy FGF signaling regulator 3.
    
 0.569
LOC103462943
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
   
   0.561
ENSPREP00000002714
SUEL-type lectin domain-containing protein.
   
   0.561
ENSPREP00000003616
Uncharacterized protein.
   
   0.561
adgrl1
Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.
   
   0.561
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.