STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lto1LTO1 maturation factor of ABCE1. (141 aa)    
Predicted Functional Partners:
yae1
OTU deubiquitinase with linear linkage specificity a.
   
 
 0.871
ENSPREP00000003924
ATP-binding cassette, sub-family E (OABP), member 1.
    
 
 0.868
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
 
 0.646
mettl25
Methyltransferase like 25.
   
  
 0.625
ano1
Anoctamin.
      
 0.616
fgf19
Fibroblast growth factor 19; Belongs to the heparin-binding growth factors family.
      
 0.598
LOC103463363
Hexosyltransferase.
      
 0.588
vps11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
   0.586
ccnd1
Cyclin D1; Belongs to the cyclin family.
      
 0.515
fgf3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.498
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.