Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103479633Protein phosphatase, Mg2+/Mn2+ dependent, 1La. (363 aa)    
Predicted Functional Partners:
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
   
 0.769
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.766
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.726
ENSPREP00000014094
NDK domain-containing protein.
  
 
 0.687
vapa
VAMP (vesicle-associated membrane protein)-associated protein A, like.
   
 0.643
LOC103464667
VAMP (vesicle-associated membrane protein)-associated protein B and C.
   
 0.643
traf7
TNF receptor-associated factor 7.
   
 0.637
ENSPREP00000027150
Uncharacterized protein.
    
   0.613
rab33b
RAB33B, member RAS oncogene family a.
   
  
 0.599
lrrc34
Leucine rich repeat containing 34.
   
 0.596
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.