STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sox8SRY-box transcription factor 8. (467 aa)    
Predicted Functional Partners:
LOC103470736
Doublesex and mab-3 related transcription factor 1.
    
 0.709
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.564
LOC103457845
Runt-related transcription factor.
   
 0.551
ENSPREP00000011180
Nuclear receptor subfamily 5, group A, member 2.
    
 0.548
egr2
Early growth response protein 2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4; Belongs to the EGR C2H2-type zinc-finger protein family.
    
 0.543
rspo1
R-spondin 1.
   
 
 0.542
runx3
Runt-related transcription factor.
   
 0.539
LOC103477443
Runt-related transcription factor.
   
 0.539
gata4
GATA binding protein 4.
    
 0.526
LOC103476608
Runt domain-containing protein.
   
 0.505
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]