Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kpna4Importin subunit alpha; Belongs to the importin alpha family. (521 aa)    
Predicted Functional Partners:
cse1l
CSE1 chromosome segregation 1-like (yeast).
   
 0.969
kpna1
Importin subunit alpha; Belongs to the importin alpha family.
  
0.944
kpnb1
Karyopherin (importin) beta 1.
   
 0.942
NFKB1
Nuclear factor kappa B subunit 1.
    
  0.939
LOC103480184
V-rel avian reticuloendotheliosis viral oncogene homolog A.
   
  0.933
kpna3
Importin subunit alpha; Belongs to the importin alpha family.
  
  
 
0.900
rcc1
Regulator of chromosome condensation 1.
   
 
 0.882
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 
 0.809
prpf19
Pre-mRNA processing factor 19.
   
   0.794
nup50
Nucleoporin 50.
   
 
 0.717
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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