STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prdx3Peroxiredoxin 3. (248 aa)    
Predicted Functional Partners:
txn2
Thioredoxin 2.
  
 0.934
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.899
srxn1
Sulfiredoxin.
   
 0.882
LOC103475974
Thioredoxin; Belongs to the thioredoxin family.
  
 0.864
LOC103475976
Thioredoxin; Belongs to the thioredoxin family.
  
 0.864
ENSPREP00000014094
NDK domain-containing protein.
  
 0.833
ENSPREP00000006378
Thioredoxin domain-containing protein.
  
 0.756
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1.
   
  
 0.755
LOC103475208
NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family.
   
  
 0.755
sod2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.718
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]