Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103468867Uncharacterized protein. (352 aa)    
Predicted Functional Partners:
nf1
Neurofibromin 1b.
    
 0.571
LOC103458407
Rap guanine nucleotide exchange factor (GEF) 4.
    
 0.557
ENSPREP00000015831
Uncharacterized protein.
   
 0.551
ENSPREP00000015870
Uncharacterized protein.
   
 0.551
ENSPREP00000015917
EH domain-containing protein.
   
 0.551
itsn2
Intersectin 2a.
   
 0.551
mapk8
Mitogen-activated protein kinase.
   
 0.551
foxred2
FAD-dependent oxidoreductase domain containing 2.
    
 
 0.518
lrrc18
Leucine rich repeat containing 18b.
    
 0.513
tsc2
TSC complex subunit 2.
    
 0.502
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (62%) [HD]