STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103462559Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (807 aa)    
Predicted Functional Partners:
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
  
  
 
0.901
syk
Tyrosine-protein kinase.
   
  
 0.884
LOC103462238
Matrix metallopeptidase 15b.
    
 0.834
LOC103478877
Matrix metallopeptidase 14b (membrane-inserted).
    
 0.834
LOC103471589
CD40 ligand; Belongs to the tumor necrosis factor family.
      
 0.804
LOC103473440
Notch receptor 1a.
   
 0.779
notch1
Notch receptor 1b.
   
 0.779
LOC103475119
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.751
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 
 0.748
LOC103462700
SIN3 transcription regulator family member Ab.
   
  
 0.731
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.