STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000002746Sortilin. (632 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
     
 0.942
nts
Neurotensin.
    
 
 0.874
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
    
 
 0.660
igf2r
Insulin-like growth factor 2 receptor.
    
 0.607
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
     
 0.593
psma4
Proteasome subunit alpha type.
    
 
 0.582
psma1
Proteasome endopeptidase complex.
    
   0.574
LOC103479568
Proteasome subunit alpha type.
 
  
   0.574
psmb1
Proteasome subunit beta.
    
   0.574
ngfr
Nerve growth factor receptor a (TNFR superfamily, member 16).
    
 
 0.529
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.