Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
piwil1Piwi-like RNA-mediated gene silencing 1; Belongs to the argonaute family. (840 aa)    
Predicted Functional Partners:
ENSPREP00000022562
Tudor domain containing 9.
   
 0.944
LOC103457790
Tudor domain containing 6.
   
 0.925
tdrkh
Tudor and KH domain containing.
   
 0.911
tdrd1
Tudor domain containing 1.
   
 0.883
ENSPREP00000026261
Uncharacterized protein.
   
 0.827
tdrd5
Uncharacterized protein.
   
 0.826
dicer1
Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.
    
 
 0.777
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family.
   
 0.742
LOC103467777
Zgc:56699.
   
 
 0.727
nanos3
Nanos homolog 3; Belongs to the nanos family.
   
 
 0.714
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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