STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103463800Calmegin. (649 aa)    
Predicted Functional Partners:
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.964
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 
 0.922
Ankrd45
ANK_REP_REGION domain-containing protein.
   
 0.907
ganab
Glucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family.
   
 0.897
LOC103479782
Calreticulin.
   
 0.889
LOC103464072
Calreticulin.
   
 0.889
mogs
Mannosyl-oligosaccharide glucosidase.
   
 
 0.877
rpn2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 
 0.841
edem1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
 
 0.839
ENSPREP00000008622
Protein disulfide isomerase family A, member 3.
   
 0.828
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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