Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000002838LHFPL tetraspan subfamily member 4a. (217 aa)    
Predicted Functional Partners:
TMC1
Transmembrane channel-like protein.
   
 0.688
LOC103465658
Uncharacterized protein.
   
 0.643
pcdh15
Protocadherin-related 15a.
   
 0.643
LOC103481331
Uncharacterized protein.
   
 0.643
GGT7
Gamma-glutamyltransferase 7.
   
   0.573
tmie
Transmembrane inner ear.
     
 0.568
CIB2
Calcium and integrin binding family member 2.
     
 0.525
LOC103466575
Calcium and integrin binding family member 2.
     
 0.525
cib3
Calcium and integrin binding family member 3.
     
 0.525
ewsr1
EWS RNA-binding protein 1b.
      
 0.488
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (12%) [HD]