kif2c protein (Poecilia reticulata) - STRING interaction network

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Predicted Interactions

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kif2c

Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (711 aa)

Predicted Functional Partners:

cdc20

0.827

kif11

0.796

ENSPREP00000023746

0.795

KIF18A

0.760

bub1b

0.735

espl1

0.705

Bub1

0.687

ENSPREP00000021048

0.687

mad2l1

0.672

LOC103460459

0.657

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bub1	ENSPREP00000021048	ENSPREP00000021030	ENSPREP00000021048	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	BUB1 N-terminal domain-containing protein.	0.847
Bub1	ENSPREP00000023746	ENSPREP00000021030	ENSPREP00000023746	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.929
Bub1	KIF18A	ENSPREP00000021030	ENSPREP00000033468	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.814
Bub1	LOC103460459	ENSPREP00000021030	ENSPREP00000026153	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.810
Bub1	bub1b	ENSPREP00000021030	ENSPREP00000032059	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.986
Bub1	cdc20	ENSPREP00000021030	ENSPREP00000004130	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cell division cycle 20 homolog.	0.987
Bub1	espl1	ENSPREP00000021030	ENSPREP00000024176	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Extra spindle pole bodies like 1, separase.	0.894
Bub1	kif11	ENSPREP00000021030	ENSPREP00000017489	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.897
Bub1	kif2c	ENSPREP00000021030	ENSPREP00000002866	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.687
Bub1	mad2l1	ENSPREP00000021030	ENSPREP00000031986	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	MAD2 mitotic arrest deficient-like 1 (yeast).	0.998
ENSPREP00000021048	Bub1	ENSPREP00000021048	ENSPREP00000021030	BUB1 N-terminal domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.847
ENSPREP00000021048	ENSPREP00000023746	ENSPREP00000021048	ENSPREP00000023746	BUB1 N-terminal domain-containing protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.929
ENSPREP00000021048	KIF18A	ENSPREP00000021048	ENSPREP00000033468	BUB1 N-terminal domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.810
ENSPREP00000021048	LOC103460459	ENSPREP00000021048	ENSPREP00000026153	BUB1 N-terminal domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.810
ENSPREP00000021048	bub1b	ENSPREP00000021048	ENSPREP00000032059	BUB1 N-terminal domain-containing protein.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.987
ENSPREP00000021048	cdc20	ENSPREP00000021048	ENSPREP00000004130	BUB1 N-terminal domain-containing protein.	Cell division cycle 20 homolog.	0.987
ENSPREP00000021048	espl1	ENSPREP00000021048	ENSPREP00000024176	BUB1 N-terminal domain-containing protein.	Extra spindle pole bodies like 1, separase.	0.894
ENSPREP00000021048	kif11	ENSPREP00000021048	ENSPREP00000017489	BUB1 N-terminal domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.897
ENSPREP00000021048	kif2c	ENSPREP00000021048	ENSPREP00000002866	BUB1 N-terminal domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.687
ENSPREP00000021048	mad2l1	ENSPREP00000021048	ENSPREP00000031986	BUB1 N-terminal domain-containing protein.	MAD2 mitotic arrest deficient-like 1 (yeast).	0.981

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033353

S-adenosylmethionine cycle

3 of 6

3.32

4.18

3.97e-06

GO:0006730

One-carbon metabolic process

3 of 34

2.56

2.9

0.00012

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004013

Adenosylhomocysteinase activity

3 of 3

3.62

5.1

2.79e-07

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:30809531

(2019) ITRAQ-Based Quantitative Proteomics Reveals the Proteome Profiles of Primary Duck Embryo Fibroblast Cells Infected with Duck Tembusu Virus.

3 of 15

2.92

3.43

3.13e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7158

Sulfur amino acid biosynthetic process, and Adenosylhomocysteinase-like

3 of 12

3.02

3.86

8.79e-06

CL:7161

Cysteine biosynthetic process, and Adenosylhomocysteinase-like

2 of 5

3.22

2.46

0.00067

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

apla00270

Cysteine and methionine metabolism

3 of 35

2.55

3.73

7.31e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR042172

Adenosylhomocysteinase-like superfamily

3 of 3

3.62

4.82

6.35e-07

IPR020082

S-adenosyl-L-homocysteine hydrolase, conserved site

3 of 3

3.62

4.82

6.35e-07

IPR015878

S-adenosyl-L-homocysteine hydrolase, NAD binding domain

3 of 3

3.62

4.82

6.35e-07

IPR000043

Adenosylhomocysteinase-like

3 of 3

3.62

4.82

6.35e-07

IPR036291

NAD(P)-binding domain superfamily

3 of 142

1.94

1.7

0.0031

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00997

S-adenosyl-L-homocysteine hydrolase, NAD binding domain

3 of 3

3.62

5.53

7.62e-08

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