Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
emx2Empty spiracles homeobox 2. (247 aa)    
Predicted Functional Partners:
lhx5
LIM homeobox 5.
    
 0.642
ENSPREP00000001616
LIM zinc-binding domain-containing protein.
    
 0.595
LOC103461327
Uncharacterized protein.
    
 0.595
lhx1
LIM homeobox 1a.
    
 0.595
RAB11FIP3
RAB11 family interacting protein 3.
      
 0.594
ctnnb1
Catenin (cadherin-associated protein), beta 1.
     
 0.581
GATA2
GATA binding protein 2.
   
 
 0.534
zmynd10
Zinc finger, MYND-type containing 10.
   
  
 0.531
polb
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
   0.505
kcng3
Potassium voltage-gated channel, subfamily G, member 3; Belongs to the potassium channel family.
      
 0.503
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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