STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pik3ap1Phosphoinositide-3-kinase adaptor protein 1. (859 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.873
nck2
Cytoplasmic protein.
    
   0.776
nck1
Cytoplasmic protein.
    
   0.776
pik3r3
Uncharacterized protein.
    
 0.701
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.701
LOC103470780
Uncharacterized protein.
    
 0.701
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.701
sarm1
Sterile alpha and TIR motif containing 1.
    
 
 0.698
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
    
 
 0.680
dapp1
Dual adaptor of phosphotyrosine and 3-phosphoinositides.
     
 0.669
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.