STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spg21SPG21 abhydrolase domain containing, maspardin. (311 aa)    
Predicted Functional Partners:
atpaf2
ATP synthase mitochondrial F1 complex assembly factor 2.
   
   0.905
shcbp1
SHC SH2-domain binding protein 1.
      
 0.854
LOC103463363
Hexosyltransferase.
      
 0.832
vamp7
Synaptobrevin-like 1; Belongs to the synaptobrevin family.
    
   0.792
spg11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.783
LOC103459313
Ig-like domain-containing protein.
      
 0.758
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.758
RAB7A
RAB7A, member RAS oncogene family.
    
   0.730
LOC103465062
RAB7a, member RAS oncogene family.
    
   0.730
LOC103474976
Spartin b.
      
 0.665
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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