STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD2APCD2 associated protein. (670 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
  0.787
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.776
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.775
LOC103477907
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.747
LOC103476312
Uncharacterized protein.
    
 0.747
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.747
nphs1
NPHS1 adhesion molecule, nephrin.
    
 0.702
ENSPREP00000004672
SH2 domain-containing protein.
    
 0.701
grb2
Growth factor receptor-bound protein 2b.
    
0.699
ubb
Uncharacterized protein.
    
  0.696
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.