Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
foxe1Forkhead box E1. (369 aa)    
Predicted Functional Partners:
ENSPREP00000020629
COesterase domain-containing protein.
    
 0.625
itpk1
Inositol-tetrakisphosphate 1-kinase b.
    
 
 0.584
msx1
Muscle segment homeobox 1a.
    
 
 0.567
siva1
SIVA1, apoptosis-inducing factor.
      
 0.531
hhex
Homeobox domain-containing protein.
      
 0.527
gpr161
G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family.
      
 0.512
LOC103476530
Homeobox protein.
   
 
 0.496
tipin
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
      
 0.490
perp
P53 apoptosis effector related to pmp22.
   
  
 0.482
slc5a5
Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.478
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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