STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (541 aa)    
Predicted Functional Partners:
LOC103463110
Kininogen 1.
     
  0.900
LOC103458452
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.783
LOC103463549
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.783
LOC103470235
Uncharacterized protein.
    
 0.783
LOC103470237
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.783
LOC103463548
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.733
LOC103473463
G protein subunit alpha 14.
    
 0.721
LOC103473464
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.721
LOC103473465
G protein subunit alpha q.
    
 0.721
gng12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.695
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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