ptch2 protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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[Homology]

Score

ptch2

Patched 2. (1491 aa)

Predicted Functional Partners:

smo

0.999

shh

0.999

dhh

0.989

LOC103461635

0.988

LOC103456683

0.988

cdon

0.985

boc

0.985

SMURF2

0.974

LOC103468522

0.974

smurf1

0.974

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103456683	boc	ENSPREP00000021783	ENSPREP00000028078	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	BOC cell adhesion associated, oncogene regulated.	0.945
LOC103456683	cdon	ENSPREP00000021783	ENSPREP00000024005	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Cell adhesion associated, oncogene regulated.	0.945
LOC103456683	ptch2	ENSPREP00000021783	ENSPREP00000003071	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 2.	0.988
LOC103456683	smo	ENSPREP00000021783	ENSPREP00000005932	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.905
LOC103461635	boc	ENSPREP00000016097	ENSPREP00000028078	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	BOC cell adhesion associated, oncogene regulated.	0.945
LOC103461635	cdon	ENSPREP00000016097	ENSPREP00000024005	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Cell adhesion associated, oncogene regulated.	0.945
LOC103461635	ptch2	ENSPREP00000016097	ENSPREP00000003071	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 2.	0.988
LOC103461635	smo	ENSPREP00000016097	ENSPREP00000005932	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.905
LOC103468522	SMURF2	ENSPREP00000022744	ENSPREP00000000295	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.900
LOC103468522	ptch2	ENSPREP00000022744	ENSPREP00000003071	E3 ubiquitin-protein ligase.	Patched 2.	0.974
LOC103468522	smo	ENSPREP00000022744	ENSPREP00000005932	E3 ubiquitin-protein ligase.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.535
LOC103468522	smurf1	ENSPREP00000022744	ENSPREP00000027271	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
SMURF2	LOC103468522	ENSPREP00000000295	ENSPREP00000022744	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.900
SMURF2	ptch2	ENSPREP00000000295	ENSPREP00000003071	E3 ubiquitin-protein ligase.	Patched 2.	0.974
SMURF2	smo	ENSPREP00000000295	ENSPREP00000005932	E3 ubiquitin-protein ligase.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.535
SMURF2	smurf1	ENSPREP00000000295	ENSPREP00000027271	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
boc	LOC103456683	ENSPREP00000028078	ENSPREP00000021783	BOC cell adhesion associated, oncogene regulated.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.945
boc	LOC103461635	ENSPREP00000028078	ENSPREP00000016097	BOC cell adhesion associated, oncogene regulated.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.945
boc	cdon	ENSPREP00000028078	ENSPREP00000024005	BOC cell adhesion associated, oncogene regulated.	Cell adhesion associated, oncogene regulated.	0.900
boc	dhh	ENSPREP00000028078	ENSPREP00000031160	BOC cell adhesion associated, oncogene regulated.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.941