STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cntlnCentlein, centrosomal protein. (1274 aa)    
Predicted Functional Partners:
lrrc45
Leucine rich repeat containing 45.
      
 0.621
crocc
Uncharacterized protein.
      
 0.549
nin
Ninein (GSK3B interacting protein).
      
 0.549
ascc3
Activating signal cointegrator 1 complex subunit 3.
      
 0.476
plk4
Polo-like kinase 4 (Drosophila).
      
 0.475
wdr5
WD repeat domain 5.
      
 0.467
sass6
SAS-6 centriolar assembly protein.
      
 0.463
nup85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
      
 0.412
cep135
Centrosomal protein 135.
    
 
 0.404
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.