STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ralgps2Ral GEF with PH domain and SH3 binding motif 2. (585 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.860
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.598
LOC103464537
Macrophage stimulating 1 receptor a.
    
 0.598
mst1r
Macrophage stimulating 1 receptor b.
    
 0.598
grap2
GRB2 related adaptor protein 2a.
   
 0.595
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
   
 0.591
SHC3
SHC adaptor protein 3.
   
 0.591
ENSPREP00000009325
GRB2 related adaptor protein b.
   
 0.570
ENSPREP00000009358
Uncharacterized protein.
   
 0.570
LOC103469145
GRB2 related adaptor protein a.
   
 0.570
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.