STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adamts14ADAM metallopeptidase with thrombospondin type 1 motif, 14. (1222 aa)    
Predicted Functional Partners:
ccbe1
Collagen and calcium binding EGF domains 1.
      
 0.670
svep1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.
   
 0.604
parp2
Poly [ADP-ribose] polymerase.
   
  
 0.593
pald1
Phosphatase domain containing paladin 1a.
   
  
 0.569
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
   
 
 0.516
stx1a
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
      
 0.503
stx1b
Syntaxin 1B; Belongs to the syntaxin family.
      
 0.503
LOC103481737
Syntaxin 4; Belongs to the syntaxin family.
      
 0.501
gdf15
TGF_BETA_2 domain-containing protein.
      
 0.496
pofut2
Protein O-fucosyltransferase 2.
     
 0.461
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.