Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000003194Kringle domain-containing protein. (52 aa)    
Predicted Functional Partners:
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.971
LOC103464537
Macrophage stimulating 1 receptor a.
    
 0.812
mst1r
Macrophage stimulating 1 receptor b.
    
 0.812
HGFAC
HGF activator.
   
 0.688
LOC103457124
Serine peptidase inhibitor, Kunitz type 1 b.
    
 0.676
spint1
Serine peptidase inhibitor, Kunitz type 1 a.
    
 0.676
egf
Epidermal growth factor.
    
 0.669
stat3
Signal transducer and activator of transcription.
    
 0.646
hpn
Hepsin; Belongs to the peptidase S1 family.
    
 0.638
gab1
GRB2-associated binding protein 1.
    
 0.637
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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