Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC103459868SERPIN domain-containing protein; Belongs to the serpin family. (416 aa)    
Predicted Functional Partners:
plg
Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.
   
 0.834
ENSPREP00000026545
Uncharacterized protein.
   
 0.834
ENSPREP00000026553
Kringle domain-containing protein.
   
 0.834
ENSPREP00000026566
Kringle domain-containing protein.
   
 0.834
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.822
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
  
 
0.809
igfals
Insulin-like growth factor binding protein, acid labile subunit.
   
 
 0.741
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
  
 
0.727
LOC103479052
Alpha-2-HS-glycoprotein 2.
   
 
 0.721
fga
Fibrinogen alpha chain.
   
 
 0.702
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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