pdcd5 protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene co-occurrence

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[Homology]

Score

pdcd5

Programmed cell death 5. (133 aa)

Predicted Functional Partners:

tcp1

0.980

cct4

0.973

cct3

0.971

cct8

0.921

tp53

0.906

cct5

0.880

pfdn1

0.845

cct7

0.829

snrpe

0.824

cct2

0.806

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cct2	cct3	ENSPREP00000008383	ENSPREP00000023193	Chaperonin containing TCP1, subunit 2 (beta).	T-complex protein 1 subunit gamma.	0.999
cct2	cct4	ENSPREP00000008383	ENSPREP00000030822	Chaperonin containing TCP1, subunit 2 (beta).	T-complex protein 1 subunit delta.	0.999
cct2	cct5	ENSPREP00000008383	ENSPREP00000021025	Chaperonin containing TCP1, subunit 2 (beta).	Chaperonin containing TCP1, subunit 5 (epsilon).	0.999
cct2	cct7	ENSPREP00000008383	ENSPREP00000001527	Chaperonin containing TCP1, subunit 2 (beta).	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
cct2	cct8	ENSPREP00000008383	ENSPREP00000022988	Chaperonin containing TCP1, subunit 2 (beta).	Chaperonin containing TCP1, subunit 8 (theta).	0.999
cct2	pdcd5	ENSPREP00000008383	ENSPREP00000003352	Chaperonin containing TCP1, subunit 2 (beta).	Programmed cell death 5.	0.806
cct2	pfdn1	ENSPREP00000008383	ENSPREP00000005498	Chaperonin containing TCP1, subunit 2 (beta).	Prefoldin subunit 1.	0.789
cct2	tcp1	ENSPREP00000008383	ENSPREP00000008359	Chaperonin containing TCP1, subunit 2 (beta).	T-complex 1.	0.999
cct2	tp53	ENSPREP00000008383	ENSPREP00000019676	Chaperonin containing TCP1, subunit 2 (beta).	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.934
cct3	cct2	ENSPREP00000023193	ENSPREP00000008383	T-complex protein 1 subunit gamma.	Chaperonin containing TCP1, subunit 2 (beta).	0.999
cct3	cct4	ENSPREP00000023193	ENSPREP00000030822	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit delta.	0.999
cct3	cct5	ENSPREP00000023193	ENSPREP00000021025	T-complex protein 1 subunit gamma.	Chaperonin containing TCP1, subunit 5 (epsilon).	0.999
cct3	cct7	ENSPREP00000023193	ENSPREP00000001527	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
cct3	cct8	ENSPREP00000023193	ENSPREP00000022988	T-complex protein 1 subunit gamma.	Chaperonin containing TCP1, subunit 8 (theta).	0.999
cct3	pdcd5	ENSPREP00000023193	ENSPREP00000003352	T-complex protein 1 subunit gamma.	Programmed cell death 5.	0.971
cct3	pfdn1	ENSPREP00000023193	ENSPREP00000005498	T-complex protein 1 subunit gamma.	Prefoldin subunit 1.	0.933
cct3	tcp1	ENSPREP00000023193	ENSPREP00000008359	T-complex protein 1 subunit gamma.	T-complex 1.	0.999
cct3	tp53	ENSPREP00000023193	ENSPREP00000019676	T-complex protein 1 subunit gamma.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.700
cct4	cct2	ENSPREP00000030822	ENSPREP00000008383	T-complex protein 1 subunit delta.	Chaperonin containing TCP1, subunit 2 (beta).	0.999
cct4	cct3	ENSPREP00000030822	ENSPREP00000023193	T-complex protein 1 subunit delta.	T-complex protein 1 subunit gamma.	0.999