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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
herpud1Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1. (382 aa)    
Predicted Functional Partners:
LOC103460384
Glutathione S-transferase theta 2; Belongs to the GST superfamily.
      
 0.566
mgst1
Microsomal glutathione S-transferase 1.2.
      
 0.532
LOC103477731
Activating transcription factor 4a.
   
 
 0.515
mgst3
Microsomal glutathione S-transferase 3a.
      
 0.477
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
   
 
 0.433
amfr
Autocrine motility factor receptor b.
   
 
 0.428
LOC103468496
Activating transcription factor 4b.
   
 
 0.422
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.